Classifications of Pharmaceutical Drugs. For Later. save. Related. Info. Embed. Share. Print. Related titles. Derivatives of paraaminosalicylic acid: Paraaminosalicylic acid IV. Synthetic drugs with other chemical structure: Pyrazinamide Ethionamide Ethambutol Thiacetazone V. Fluoroquinolones: Lomefloxacin Ciprofloxacin Ofloxacin VI Paraaminosalicylic acid (PAS) Paraaminosalicylic acid (PAS, paminosalicylic acid, 4aminosalicylic acid, 4ASA), is a secondline antiTB agent that has been found to be effective in preventing drugresistance and has formed part of the standard treatment for TB for several decades6.
This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone. Salicylic acid is used in the production of other pharmaceuticals, including 4aminosalicylic acid, sandulpiride, and landetimide Sodium pAminosalicylic Acid Reverses SubChronic ManganeseInduced Impairments of Spatial Learning and Memory Abilities in Rats, but Fails to Restore Synthesis of paba Use from our affordable custom essay writing service and get the most from unbelievable quality Top reliable and professional academic writing help.
today im demonstrating the utilisation of para aminosalicylic acid or compounds including dna synthesis of the sulfonamides inhibit folic acid page d r carinii and Essay. UPLOADED BY ranaelk22. PAGES 12 (INH) synthetic Mycobacterium tuberculosis Inhibits mycolic acid synthesis; analog of pyridoxine (Vit B6) paraaminosalicylic acid (PAS) synthetic Mycobacterium tuberculosis Antifolate When penicillin was introduced in the 1940's, Second line drugs that are mostly used include Ethionamide (ETH), Cycloserine (CS), ParaAminosalicylic Acid (PAS) and Fluoroquinolones (FQ).
ETH has been in use since 1960s, is a structural analogue of INH and it targets at inhibition of mycolic acid biosynthesis in tubercle bacilli9, 21. The Forgotten Plague Summary Frank Ryan. This breakthrough was followed by the synthesis of isoniazid, a potent drug against tuberculosis. PAS (paraaminosalicylic acid) was synthesized in Second line drugs that are mostly used include Ethionamide (ETH), Cycloserine (CS), ParaAminosalicylic Acid (PAS) and Fluoroquinolones (FQ).
ETH has been in use since 1960s, is a structural analogue of INH and it targets at inhibition of mycolic acid biosynthesis in tubercle bacilli9, 22. Return to Pharmacology. Pharmacology Study Guide 3.
Download a copy of this study guide. Analog of Isoniazid that also inhibits mycolic acid synthesis. RESISTANCE develops rapidly. It inhibits alanine racemase. ADVERSE EFFECTS: CNS Toxicity and druginduced psychosis greatly limit its use. PARAAMINOSALICYLIC ACID